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br Funding br The author s disclosed
2022-05-25
Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was partly supported by a Grant-in-Aid for Niigata University of Health and Welfare, as well as the M.D. Anderson Cancer Center Support Grant C
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br P was defined as a tumor invasion
2022-05-23
P0 was defined as a tumor invasion depth restricted to the M or SM1, and P1 was defined as an invasion depth deeper than the SM1. If gastric cancer was diagnosed as P0 before treatment, it was deemed suitable for endo-scopic resection if other clinical parameters met the guide-lines. By contrast,
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br and MMP were dramatically decreased after treatments with CNC
2022-05-22
and MMP-9 were dramatically decreased after treatments with CNC, in-dicating that CNC could suppress cell metastasis by inhibiting activities of MMPs. The relatively quantitative levels of MMP-2 and MMP-9 were shown in Fig. 7B. The expressions of apoptosis related proteins were subsequently detect
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br centrifuged at g for min
2022-05-22
centrifuged at 10000 g for 15 min at 4 °C and supernatants were col-lected. The concentrations of total protein were assessed with the BCA protein assay kit. Equal amounts of protein in the cell extracts were sep-arated by 12.5% sodium dodecyl sulfate-polyacrylamide gel electropho-resis (SDS-PAGE)
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br on the surface of LDHs
2022-05-22
on the surface of LDHs, and thus the LDH particles have a surface po-sitive charge. After placing a part of L-Dopa inside the layers and on the surface of [email protected], the negative charge on the surface in-creases which cause smaller zeta potential in [email protected]@L-Dopa (Fig. 11a). In
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br Mice model and in vivo tumor
2022-05-22
2.8. Mice model and in vivo tumor xenograft assays This study was approved by the Animal Care and Use Committee of the Universidad Autonoma de Madrid (UAM) in accordance with the EU Directive 2010/63/EU for animal experiments. Animals were housed under pathogen-free conditions in the Animal Res
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b iframe width height src https
2022-05-20
r> For the immunoprecipitation assay, cell lysates (600 μg) were im-munoprecipitated with protein A/G agarose beads (Merck Millipore, Temecula, CA, USA) which mixed with 1 μg of anti-acetyl-lysine anti-body in Fig. 3A, Hsp90 antibody in Fig. 3B and F-actin antibody in Fig. 5C, respectively. The pre
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An RIT containing an anti CD
2022-05-20
An RIT containing an anti-CD22 Fv fragment, clinically iden-tified as Moxetumomab pasudotox, has shown considerable efficacy in phase I and phase III studies in drug-refractory hairy cell leu-kemia, including a 64% complete response rate and an 88% overall response rate.2,3 Moxetumomab pasudotox is
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br Results and discussion br Preparation and characterization
2022-05-19
3. Results and discussion 3.1. Preparation and characterization of Eu(III) complex- and DPY-conjugated nanocellulose hydrogel coordinated with europium ion to form Eu(III) complex-CMC, the C=O group bands were blue-shifted to 1732 cm−1, and the carbonyl stretching at 1654 cm−1 disappeared. I
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br Biochemical analysis of saliva samples br
2022-05-18
2.6. Biochemical analysis of saliva samples All saliva samples were evaluated for the level of acyl hydroper-oxides [70]. To do that, 0.200 mL of saliva were placed in a separate tube, where 4 mL of heptane-isopropanol mixture (1:1) were added, and the contents were shaken for 10–15 min. Then,
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br Prior studies suggest symptomatic relapses may occur in
2022-05-18
Prior studies suggest symptomatic relapses may occur in 40% to 76% of NSCLC patients.8,15,16 In our study, 56% of patients with relapse sought medical attention as a result of relapse-related symptoms before scheduled surveillance imaging. We observed no differences in the median onset of any rela
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Talanta br journal homepage www
2022-05-17
Talanta journal homepage: www.elsevier.com/locate/talanta An ssDNA aptamer selected by Cell-SELEX for the targeted imaging of poorly T differentiated gastric cancer tissue Wanming Lia, Shuo Wanga,b, Linlin Zhoua, Yajie Chenga, Jin Fanga, a Department of cell Biology, Key Laboratory of C
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br Chemicals and statistical analysis br All chemicals
2022-05-17
2.9. Chemicals and statistical analysis All chemicals used in this study were obtained from Sigma-Aldrich (St. Louis, MO, USA) unless otherwise stated. PDMP was purchased from Matreya (State College, PA, USA). (−)-Neplanocin A (NPC), which was demonstrated to block m6A formation by acting as a
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br Table Descriptive statistics of
2022-05-15
Table 2. Descriptive statistics of the DISCERN items DISCERN factors and items n mean SD Reliability Clear when information was produced 55 2.7 1.3 Details of additional sources 55 3.8 1.5 Treatment Choices Describes how treatments work 55 1.7 1.1 Describes benefit
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Cy5.5 NHS ester br Fig Calculation of combination index CI
2022-05-13
Fig. 1. Calculation of combination index (CI) of combined treatment of 5-FU and rapamycin in colon cancer cell lines. A. Dose-effect curve for LoVo cells. B. Fa-Cl plot for LoVo cells. C. Dose-effect curve for sw480 cells. D. Fa-Cl plot for sw480 cells. Fig. 2. Synergistic effect of combination