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br Heparan sulfate O endosulfatase gene SULF encodes an
2020-08-06
Heparan sulfate 6-O-endosulfatase gene (SULF2) encodes an oncoprotein with heparin-degrading endosulfatase activity, which activates receptor tyrosine kinases and downstream pathways including MAPK, AKT, and WNT [33]. While the role of SULF2 methylation has been mostly unknown in CRC, SULF2 methyl
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br The average follow up time in
2020-08-06
The average follow-up time in the REGARDS sub-cohort was 8 years (SD = 3.3). Figs. 2 and 3 present the survival probabilities by tertiles of IL-6 and resistin, respectively. Tests of interaction between assessed bio-markers and BMI were statistically significant, p-values b0.05. Among participants
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br Corfield J Perera M Bolton
2020-08-04
15. Corfield J, Perera M, Bolton D, Lawrentschuk N. 68 Ga-prostate specific membrane antigen (PSMA) positron emission tomography (PET) for primary staging of high-risk prostate cancer: a systematic review. World J Urol. 2018;36:519–27. 16. Afshar-Oromieh A, Haberkorn U, Eder M, Eisenhut M, Zech
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br Prior to the endoscopic procedure all patients underwent
2020-08-04
Prior to the endoscopic procedure, all patients underwent high-resolution mUS assessment in a lithotomic position. Micro-US imaging was performed using the ExactVu system with an EV29L 29-MHz side-fire transducer (Exact Imaging, Markham, Canada). Two urologists (G.L. The procedure was feasible
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br The e ects of
2020-08-03
The effects of these 22 fractions on three different tumor Norfloxacin of digestive system and CIK cells were observed by microscope. Four ca-tegories of fractions were divided: (a) fractions promoted growth of tumor cells and CIK cells, namely F1; (b) fractions inhibited growth of tumor cells and
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Dexmedetomidine br Introduction br Cancer is one of the worl
2020-08-02
1. Introduction Cancer is one of the world's most fatal diseases, which annually > 10 million new cases have added to its patient population. Therefore, development of therapeutic approaches, that mainly involves re-searches on pharmaceutical systems, is necessary. Nowadays, 3,4-dihydroxy
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br specimens p x The prognostic value
2020-07-28
specimens (p=2.3x10-6). The prognostic value of miR-196a expression has not been tested in our study, however, it has been shown recently that high levels of miR-196 as a plasma biomarker is associated with dismal survival in pancreatic adenocarcinoma patients [29]. ROC analyses for the miR-196a m
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br dt br K br K br Because this
2020-07-28
dt K K Because this is a system of ordinary differential equations, the global convergence of its solutions can be achieved through qualitative analysis. Set Q and The results concerning the existence of equilibria and their stability are stated in the following theorems. The pro
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br This e learning program can be accessed on the
2020-07-28
This e-learning program can be accessed on the web. Therefore, it is possible to educate many endoscopists on the diagnosis process of M-NBI, and it is expected that the web program will be widely provided in the future. Based on the results of this study, a good learning effect on the e-learning
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br Usefulness assessments were completed
2020-07-27
Usefulness assessments were completed using a 33-item checklist of cancer caregivers’ unmet supportive care needs based on a systematic review by Lambert et al. (2012) [5]. The six domains evaluated include: comprehensive cancer care, emotional and psychological, caregiver impact and daily activi
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br Microfludic chips are usually compared with traditional T
2020-07-06
Microfludic chips are usually compared with traditional Tran-swell when it comes to the in vitro research methodology platform. Here we both applied the chip we build and Transwell to investi-gating the effect of AKR1B10 on the trans-BBB capacity of (±)-Baclofen metastasis lung cancer cells. On th
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b iframe width height src https www youtube
2020-07-04
r> 3. Results Our underserved population comprised 4808 adults diagnosed with a first primary invasive solid tumor between January 1, 2008 and December 31, 2015 (Fig. 1). Table 1 summarizes the overall and in-tervention-stratified distribution of patient characteristics. Racial/ ethnic minoritie
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br Targeting metabolism of DHEAS to DHEA with STS
2020-07-04
Targeting metabolism of DHEAS to DHEA with STS inhibitors, such as STX64, has been proposed as a new approach to treat sex hormone-related cancers, including breast cancer and PCa, and have been tested in phase I and phase II clinical trials (Woo et al., 2011; Williams, 2013; Day et al., 200
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Luteolin br DFS and OS rates br The patient survival
2020-03-24
DFS and OS rates The patient survival rates were evaluated during a median follow-up Luteolin of 56 mo (range: 6-180 mo). There was no significant difference in OS and DFS between the CHT/ET and ET-alone groups (P ¼ 0.416 and 0.210, respectively, Fig. 3). Given that the CHT/ET group had more r
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br Fig Activin A downregulates E cadherin
2020-03-24
Fig. 1. Activin A downregulates E-cadherin in human ovarian cancer cells. Y. Yi, et al. Experimental Cell Research xxx (xxxx) xxx–xxx Fig. 2. Activin A downregulates E-cadherin through the ALK4 receptor in SKOV3 cells. 3.3. Activin a upregulates SNAIL and SLUG expression in human ovarian