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br Numerical simulations br In this section
2019-09-24
4. Numerical simulations In this section, we complete the theoretical analysis with nu-merical simulations of system (3) showing how the patterning be-havior of solution changes depending only on few parameters, as commented in the previous sections. All simulations have been performed with the
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br SPF showed overall greater accuracy and
2019-09-24
SPF showed overall greater accuracy and lower computational time with respect to classical variational level set methods, essen-tially thanks to its ability to escape local minima and converge faster (Abdelsamea & Tsaftaris, 2013). However, as a global level set method which does not exploit prior
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br AJCC stage groupings br
2019-09-23
3.2. AJCC stage groupings 3.3. Modified prognostic groupings Based on the aforementioned findings, an optimized staging system was constructed. Herein, the pT4aN0M0 category was incorporated into the modified stage IIIA from stage IIB, because its survival data mat-ched with stage IIIA. As o
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br This property is equivalent to the statement that
2019-09-23
This property is equivalent to the statement that for some data sample, in the E-step of each iteration, a non-null mem-bership assignment is more likely to be assigned a higher confidence. To formally address this statement, the following lemma is introduced: Now we turn to the proof of Proper
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br The sti ness Fig d
2019-09-16
The stiffness (Fig. 1d and S2) and compressive strength (Supplemental Table 1) of the three CA scaffold compositions were measured in dry and wet states. Two stiffness values, bulk stiffness and wall stiffness, were obtained due to the porous structure of the CA Biomaterials 217 (2019) 119311 a
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IEEE Trans Biomed Eng br Kuenen MP Mischi
2019-09-16
IEEE Trans Biomed Eng 2014;61:1–11. Kuenen MP, Mischi M, Wijkstra H. Contrast-ultrasound diffusion imaging for localization of prostate cancer. IEEE Trans Med Imag-ing 2011;30:1493. Kuenen MPJ, Saidov TA, Wijkstra H, de la Rosette JJMCH, Mischi M. Spatiotemporal correlation of ultrasound Ko 14
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br In the cell uptake studies F
2019-09-16
In the cell uptake studies, [18F]FPTT showed higher uptake in PR-positive MCF-7 Filipin III than in PR-negative MDA-MB-231 cells, and could be specifically inhibited. Especially, the uptake of [18F]FPTT in PR-negative MDA-MB-231 cells with or without PR inhibitor was not signif-icantly different.
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br Of the patients were male Table Median
2019-09-16
Of the 36 patients, 18 were male (Table 1). Median age at diagnosis was 61.5 years (range, 39-78 years). Mean IMRT dose was 54.8 Gy ±2.9 Gy. The clinical stage and KPS of pre-CRT and post-CRT are shown in Table 1. T-test results indicate that there was no significant difference between patient coh
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br We have now developed a novel framework
2019-09-16
We have now developed a novel framework for the prediction of the prognosis of breast cancer patients (Fig. 1). We first examined all protein-coding genes for their relation to OS in breast cancer patients. We then validated 184 prognosis-related genes by meta-analysis of Please cite this artic
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Gilteritinib Patients with NSCLC experience symptoms that co
2019-09-02
Patients with NSCLC experience symptoms that Gilteritinib commonly include dyspnea, cough, fatigue, anorexia, and pain, which affect the physical as well as functional aspects of a patient’s QoL [[14], [15], [16]]. Symptom burden is significantly higher in patients with more advanced NSCLC [17] and
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br Disclosures br Introduction Survivals of advanced anaplas
2019-09-02
Disclosures Introduction Survivals of advanced anaplastic lymphoma kinase (ALK-positive) non-small cell lung cancer (NSCLC) patients have dramatically changed since the development of efficient ALK tyrosine kinase inhibitors (TKi). However, ALK-positive patients seem to relapse more commonly i
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In the present study there was no association with OS
2019-08-26
In the present study, there was no association with OS and development of irAE with 3-, 6-, and 9-month landmark analysis. Landmark analysis was utilized in order to minimize lead- time bias associated with time-dependent factors. Studies involving nivolumab treated aNSCLC patients utilized landmark
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At this time progressive hilar disease was
2019-08-26
At this time, progressive hilar disease was biopsied, confirming TTF-1 positive adenocarcinoma, ALK positive by IHC (ALK1); next generation sequencing (NGS) further confirmed an EML4-ALK fusion with no additional kinase mutations, but sample was insufficient to identify other somatic variants. He th
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ctDNA is released by passive mechanisms such as lysis
2019-08-26
ctDNA is released by passive mechanisms, such as lysis of apoptotic and necrotic Thapsigargin or digestion of tumor cells by macrophages, and also by active mechanisms. ctDNA shows an enrichment in 150–180 bp fragments, typical of the nucleosomal pattern of DNA fragmentation during apoptosis. Most
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We found a dose response association between higher
2019-08-26
We found a dose-response association between higher birth order and risk of childhood N-octanoyl-L-Homoserine lactone tumors. Previous case-control studies have reported similar results for overall childhood brain tumors [11,[28], [29], [30], [31]] and particularly for astrocytomas [28], and embryo